ethyl trans-1-benzyl-4-(3-ethoxy-4-methoxyphenyl)pyrrolidine-3-carboxylate - Names and Identifiers
ethyl trans-1-benzyl-4-(3-ethoxy-4-methoxyphenyl)pyrrolidine-3-carboxylate - Introduction
ethyl trans-1-benzyl-4-(3-ethoxy-4-methoxyyl) pyrrolidine-3-carboxylate is a compound commonly abbreviated as EBMP. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- EBMP is a colorless to pale yellow liquid.
-It has a fragrant smell.
- EBMP has a density of 1.11g/cm³.
-Its boiling point is 370-372 ℃.
- EBMP is insoluble in water at room temperature, but is readily soluble in organic solvents such as methanol and dichloromethane.
Use:
- EBMP is an organic synthetic intermediate with biological activity, which is widely used in the fields of medicine and pesticide.
-It can be used as a precursor compound for anti-cancer drugs, antiviral drugs and antidepressants in the drug development process.
- EBMP can also be used to prepare pesticides with anti-inflammatory, antifungal and antiviral activities.
Method:
The preparation method of-EBMP is relatively complicated, usually through a multi-step reaction.
-A possible synthesis method is to react benzylamine with ethyl 2-bromoacetate to obtain 1-benzyl -2-(2-carbonylethyl) pyrrolidine. It is then reacted with P-methoxyphenol in the presence of a base to give 1-benzyl -4-(3-methoxyphenyl) pyrrolidine. Finally, the final product EBMP was prepared by ethyl acetate acidolysis and N-benzylation.
Safety Information:
- EBMP is a chemical and should be used in accordance with appropriate laboratory procedures.
-Wear appropriate protective equipment such as gloves and goggles when handling EBMP.
- EBMP may be irritating and corrosive to eyes and skin, avoid direct contact or inhalation.
-When using or storing EBMP, care should be taken to avoid fire and avoid ingestion.
-If you accidentally swallow or come into contact with EBMP, seek medical help immediately and bring packaging for reference.
Last Update：2024-04-09 21:00:56